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The number of infiltrating cells in the 50% dosage group was lower than that of the 25% dosage group in the asthma prevention experiment.
The surfaces of the lungs of the mice in the prevention experiment were inspected for the presence of metastatic 4T1 tumors.
The livers of mice in the prevention experiment were sectioned and stained, and the numbers of metastatic nodules inside the livers were counted.
Similar results were obtained as in the prevention experiment, where the Fe-Lf and tamoxifen therapies each significantly (P < 0.05) suppressed the growth of tumors.
4T1 breast tumors were collected from mice in the prevention experiment which had been fed for 28 days with the control diet or the Fe-Lf diet.
While the latter result did not reach statistical significance, there was a clear trend toward decreased tumor multiplicity throughout the course of the prevention experiment.
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RAL codesigned the prevention experiments and revised the manuscript.
Macrophage foam cell prevention experiments were initiated 48 h after transfection.
JDH assisted in designing and performing the prevention experiments and revised the manuscript.
MNG conceived, codesigned, and coordinated the prevention experiments and revised the manuscript.
Osmotic pump administration was conducted in a similar manner as for the prevention experiments.
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