Sentence examples for preventing differentiation from inspiring English sources

Decreased expression of these molecules may result in expansion of primitive tumorgenic cells by preventing differentiation.

This TF maintains self-renewal and pluripotency, preventing differentiation in embryonic [69] and neuronal stem cells [70].

However, lif expression could also be important later in tumorigenesis, perhaps even in tumor maintenance, as a mechanism for preventing differentiation of neuroblastoma.

Notch/RBP-J signaling activates Hes/Hey transcription, which leads to repression of Hes/Hey target genes such as tissue-specific transcriptional activators, thereby preventing differentiation [5].

Thus, the immune mechanisms preventing differentiation of anergic B cells to late pre-plasma and Ab-forming cells are defective in NZB mice.

Further to this, Nodal acts in parallel with FGF4, to maintain normal expression of Errβ, Eomes and Cdx2, thereby preventing differentiation of TS cells [56].

For the Greeks, art as well as religion supplied the connective tissue that prevents differentiation from pulling human life to pieces.

In contrast, heparan sulfate did not prevent differentiation marker expressions.

In vitro studies showed that 1,25-dihydroxyvitamin D could prevent differentiation of dendritic cells and modulates T cell phenotype and function [19].

The NAD+-dependent sirtuin SIRT6 is highly expressed in human breast, prostate, and skin cancer where it mediates resistance to cytotoxic agents and prevents differentiation.

Moreover, our results show that Notch signaling is necessary to prevent differentiation of melanocyte stem cells and of melanoblasts before they reach the hair bulb.