Sentence examples for preventing cell cycle progression from inspiring English sources

Chk1 and Chk2 negatively regulate the Cdc25 family of phosphatases thereby preventing cell cycle progression as well as directly modulating repair proteins resulting in increased lesion repair.

Perhaps, up-regulation of male-specific miRNA, including the let-7 family, may play a role in preventing cell cycle progression despite high levels of expression of miR-17-92 miR-17-92 miR-17-92

p16 inhibits CDK4, keeping RB hypophosphorylated and preventing cell cycle progression.

Atiprimod blocked U266-B1 myeloma cells in the G0/G1 phase, preventing cell cycle progression.

These oxylipins can inhibit cell division by preventing cell cycle progression [ 50, 51], and repressing mitosis-phase genes [ 52].

Transforming growth factor (TGF -β suppresses breasTGF -βer formation by preventing cell cycle progresuppressesammary epithelial cells (MECs).

Disorganized tubulin polymerization prevents cell cycle progression.

This was made possible since the expression of the chimeric proteins did not prevent cell cycle progression.

Specifically, p21 prevents cell cycle progression from G1 to S phase by inactivating the Cdk2-cyclin E complexes, that, in turn, inhibit the tumor suppressor protein retinoblastoma (pRb) required for entering S-phase[23].

Although diploid ctf4Δ mutants appear to be competent for spontaneous recombinational repair [40], (Fig. 3A) damage-induced recombination may be compromised [54] suggesting that diploid ctf4Δ mutants may have persistent DOX-induced DNA damage that elicits a prolonged G1 arrest signal that prevents cell cycle progression similar to that seen for rad51Δ cells at high DOX doses (Fig. 1C).

P21WAF1 prevents cell cycle progression at the G1 phase.