Sentence examples for prevent remodelling from inspiring English sources

However, it is unclear if specific aldosterone antagonism is also able to prevent remodelling and stiffening of resistance arteries in this model of diabetes mellitus.

However, morbidity and mortality of HF still remain high, indicating that we have not yet fully grasped the mechanisms of the underlying pathology and are not able to prevent remodelling.

Long Beach, which has 17 historic districts including Bluff Park, received an A. Linda Dishman, the conservancy's executive director, said districts aren't trying to prevent remodeling.

The anticipated objective of our multipronged strategy was to achieve intracrine, autocrine, and paracrine effects of Shh protein which was secreted from MSCs overexpressing Shh (ShhMSCs) and regenerated the damaged tissue, induced revascularization and concomitantly prevented remodeling of the heart by preserving the existing myocardium.

In another report, PHD inhibitors did not reduce infarct size, but improved left ventricular function and prevented remodeling [ 44].

In contrast to a typical pro-fibrogenic signature, with evidence of increased myofibroblast activation and collagen production, Timp1 mRNA, encoding a key hepatic Mmp inhibitor that prevents remodelling of the fibrotic scar [ 61, 62], was increased in LysM-Wls mice compared to littermate controls in both the TAA and CDE models.

Although pharmacological strategies for established heart failure can be beneficial, preventing remodeling remains a challenge.

The lower CPR levels due to atorvastatin treatment suggest that atorvastatin helps in preventing remodeling of atrial electricity and structure and inhibits the inflammatory process to prevent the development of AF [ 21].

Since systemic LXR activation may exert many roles in the pathogenesis of the aforementioned co-morbidities, targeting of LXRs during this phase may serve as a useful addendum in preventing remodeling progression.

These results differ from those of Wakeno and colleagues [8], where a selective adenosine A2B receptor agonist was reported to prevent LV remodelling after MI.

Most importantly, transplanted graft cells should improve cardiac function and prevent ventricular remodelling.