Sentence examples for prevent reactivation from inspiring English sources
For instance, the use of INH only in preventive therapy, especially in HIV-infected individuals, might not be sufficient to prevent reactivation of latent infection of the adipose tissue.
Thus, it is important to design new vaccines to prevent reactivation.
Available antiviral therapies do not affect latent viral genomes; therefore, they do not prevent reactivation following therapy cessation.
In addition, INH has been used as a prophylactic drug for individuals with latent Mycobacterium tuberculosis (MTB) infection to prevent reactivation of disease.
It is plausible to assume that the best strategy to handle CMV disease in the ICU is to prevent reactivation in seropositive patients as these are at high risk of developing the disease.
In vivo, there is evidence that type II IFN (IFNgamma), mainly produced by CD8+ T lymphocytes, plays only a minor additional role to type I IFNs in controlling early acute infection [45], [46] but is important to prevent reactivation of alphaherpesviruses from latency [31], [47].
"Cytomegalovirus Control in Critical Care trial" (NCT01503918) is addressing the safety and success rate regarding preventing reactivation of latent cytomegalovirus infection in critically ill patients when treated with one of two different antiviral regimens: "Valaciclovir/Aciclovir or not".
Expression of a constitutively active form of MEK MAPP kinase kinase), which prevented the normal downregulation of MAPK after egg activation, also prevented reactivation of HCO3−/Cl− exchange.
Although speculative at this point, together with the literature data, this may suggest that especially type I IFNs, as a crucial factor of the innate antiviral immunity, may be of importance during establishment of latency whereas type II IFN produced by the adaptive immunity are of crucial importance in maintaining the virus in a latent state and preventing reactivation.
The inhibitory lipid prevents reactivation of inactive nucleation sites, which accumulate during the pre-incubation (va < vi).
Could a reduction in potentially protective immune responses increase vulnerability upon re-exposure, possibly out-weighing the benefit of preventing reactivation of latent infection?
