Sentence examples for prevent cell proliferation from inspiring English sources

Various natural products and synthetic molecules have been designed to prevent cell proliferation.

The percentage of cell survival as a function of drug concentration was plotted to determine the drug concentration needed to prevent cell proliferation by 50% (IC50).

We here show that meridianins inhibit various protein kinases such as cyclin-dependent kinases, glycogen synthase kinase-3, cyclic nucleotide-dependent kinases and casein kinase 1. Meridianins prevent cell proliferation and induce apoptosis, a demonstration of their ability to enter cells and to interfere with the activity of kinases important for cell division and cell death.

The percentage of cell survival as a function of drug concentration was then plotted to determine the IC50 value (the drug concentration needed to prevent cell proliferation by 50%) [18], [24].

Taken together, out results are consistent with a model where EF-G1 may function as a retrograde signal from mitochondria to the nucleus to prevent cell proliferation, if mitochondrial ATP synthesis is too low.

Cytosine β-D-arabinofuranoside hydrochloride (Sigma) (10 µM), a selective inhibitor of DNA synthesis which does not inhibit RNA synthesis was used 1 h before the test substance was added to prevent cell proliferation.

Several studies have shown that COX inhibition prevents cell proliferation and promotes apoptosis.

The majority of anticancer agents including celecoxib interact with nuclear DNA to cause DNA damage thus preventing cell proliferation and inducing apoptosis (Wei et al. 2008; Danhier et al. 2009; Jung et al. 2009; Munoz-Bonilla et al. 2009; Yuan et al. 2010).

It has been unclear, however, whether the inhibition of caspase activities prevents cell proliferation.

Blocking the Wnt/ β-catenin pathway prevents cell proliferation and results in apoptosis or necrosis.

Growth arrest by p21 can promote cellular differentiation, and therefore prevents cell proliferation [ 23].