Sentence examples for prevent cell differentiation from inspiring English sources
In addition, the new method was able to prevent cell differentiation effectively and retain the characteristics of stem cells.
This pathway, which requires the cytoplasmic protein Deltex, appears to prevent cell differentiation.
Their results showed that FXYD-3 silencing had no effect on cell proliferation but could promote cell apoptosis and prevent cell differentiation of Caco-2 cells.
The reduction of both nutrient acquisition and electrolyte secretion indicates that L. intracellularis may be able to prevent cell differentiation in immature enterocytes.
Since exogenous NANOG expression can sustain pluripotency in ES cells [ 12, 18], it would be interesting to determine if RNAa-mediated overexpression of NANOG can also prevent cell differentiation.
Taken together, the concerted activity of Notch/BMP and downstream genes of the network here presented may not merely prevent cell differentiation and maintain the progenitor state, but rather actively modulate cell fate choices in the DM.
Briefly, ES cells were kept in standard ES cell medium containing leukemia inhibitory factor (LIF) which prevents cell differentiation.
Furthermore, DUX4c expression inhibited MYOD1 DNA-binding activity and prevented cell differentiation following serum withdrawal, as reported for Myf5+/MyoD− myoblasts [31] and in iC2C12-DUX4c cells [28].
Notch activation in muscle progenitors impairs the transcription of myogenic factors, preventing cell differentiation and promoting proliferation.
In embryonic development, it is involved in maintaining the pluripotent ICM (inner cell mass), sustaining the epiblast and preventing cell differentiation [ 12– 15].
It also makes its neighbors or non-descendent modules close (shown as ③ in Fig 3), which maintains the identity of the cell and prevents cell differentiation.
