Sexual dysfunction has only recently been recognized as a highly prevalent side effect of adjuvant aromatase inhibitor (AI) therapy for breast cancer.
Everolimus was also well tolerated, skin toxicity being the most prevalent side effect.
Diarrhea was the most prevalent side effect, but its frequency did not statistically significantly differ between placebo and plecanatide, and appeared not to be dose-related in the plecanatide-treated subjects.
Notwithstanding, FTM has been shown to cross the blood-brain barrier because of its lipophilic profile and in the population of patients with recurrent GBM demonstrated a good activity and a favorable safety profile, mielosuppression being the most prevalent side effect [ 4– 8].
Clinical trials using synthetic KATP channel openers report headache as a prevalent-side effect in non-migraine sufferers, indicating that KATP channel opening may cause headache, possibly due to vascular mechanisms.
Although for many years it was believed that the prevalent EPS side effects and the therapeutic effects of antipsychotic drugs could not be dissociated since the former effects were assumed to be required for the latter effects [ 33, 59], the recent introduction of more specific second generation antipsychotic drugs implied otherwise [ 33, 60].
One of the most prevalent long-term side effects of cancer treatment in boys is infertility.
The remaining 33 patients (group 2) refused AR based on different social and cultural backgrounds, such as how far they lived from the institute (sometimes more than 500 KM) and some prevalent exaggerated concerns about the side effects of radiotherapy, sometimes potentiated by personal previous experience of a relative of the patient.
Insomnia is a prevalent and persistent side effect of cancer, which if left unaddressed, can be unremitting and negatively influence physical and mental well-being.
