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In all, 98 samples were collected before RA diagnosis (incident samples) and 123 were collected after diagnosis (prevalent samples).
For both samples the barcode CCTT was most prevalent (Sample 1: 9,889,602; Sample 2: 16,368,793), and for both samples the barcode CGCT was the least common (Sample 1: 2,991,820; Sample 2: 5,002,346).
Human blood, human liver, mouse brain and mouse liver are the most prevalent samples used (Supplementary Table S6).
A higher cost setup for the rare samples than that for the prevalent samples means that more weights will be boosted on the rare samples.
Studies of delayed discharge have been performed both in samples of long-stay patients and in prevalent samples of psychiatric inpatients.
The secondary objective, again replicating the method used by Prescott et al., was to assess the growth in medical and drug costs over time by comparing aggregated cost data for prevalent samples in 2006 and 2011.
Among various prevalent samples of psychiatric inpatients, the proportion classified as being a delayed discharge either due to lack of housing or to which lack of suitable housing contributed was 356/227 (15%) [ 23], 396/3710 (11%) [ 24] in two London-based studies; and 289/2236 (13%) [ 25] in a national survey.
Subtype assignments into of samples to good and bad prognosis were also prevalent for samples in the additional validation study, however, in this dataset contamination of cancer signatures in normal samples was also present (Additional file 1: Text S1).
Amplifications of EGFR were more prevalent in samples with at least one fusion compared to samples with no fusions (63% vs. 38%, p = 0.0016, Fisher's exact test).
