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The prevalence of selection was far greater in wMel than wBm.
The prevalence of selection on genes encoding heat shock proteins is higher in wMel than in wBm.
The prevalence of selection was roughly equal in wBm and wMel (six vs. nine genes, respectively) and could represent another strategy for minimizing effects of other sources of error on protein performance.
Despite these similarities (showing, for instance, a prevalence of selection against mutations in the framework region of Ig V genes, which is not seen in controls), we are well aware that altered mutation patterns in the Ig V gene regions in themselves are not sufficient to indicate autoreactivity in the granulomatous inflammation.
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These methods rely on screening for silent variants to obtain estimates of the background mutation prevalence, independent of selection.
Indeed, our recent work on a small subset of honey bee genes associated with worker behavior has shown a prevalence of natural selection and high linkage disequilibrium near selective sweeps.
Despite this longstanding interest, the prevalence of disruptive selection in natural populations, and therefore the relative importance of disruptive selection in generating biological diversity, remains unclear.
The prevalence of purifying selection in these bacteria is similar to the apparently strong purifying selection acting against the majority of duplications and structural variants in model eukaryotes (Emerson et al. 2008; Cridland and Thornton 2010; Li et al. 2011).
The above results could be explained if sexual selection drives the evolution of many male-biased genes and the prevalence of sexual selection differs between the two subgroups.
Similarly, the extent of hitch-hiking is controlled by the proportion of sites with weak deleterious effects relative to the strength of positive selection, with the specific range varying according to the strength and prevalence of positive selection.
While sex-selective abortion is common in some Asian countries, it is not clear whether the legal status of abortion is associated with the prevalence of sex-selection when sex-selection is illegal.
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