Understanding the nature of the resistance mechanism s), natural prevalence of resistant mutants and their fitness and persistence will allow a better design of treatment options.
We used population-based data to evaluate how often groups of randomly selected clinical laboratories accurately estimated the prevalence of resistant pneumococci and captured trends in resistance over time.
155– 159 Similarly cogent evidence of a fitness cost to resistance has been demonstrated by decreased prevalence of resistant parasites after the dry season in west Africa, when there is relatively little drug selection pressure.
There are increased patterns of antimicrobial resistance secondary to multiple antibiotic exposures and increased prevalence of resistant bacteria within the community, particularly S. aureus.
Studies comparing bacterial resistance in various European countries have clearly documented that the prevalence of resistant strains is correlated with the consumption of antibiotics [ 4, 13].
The aim would be to help monitor the prevalence of resistant virus and changes in its geographic distribution for public health purposes and guide therapy for infected people.
We also discussed the relationship of long-term antibiotic use and the prevalence of resistant pathogens.
Due to the increased prevalence of resistant bacterial isolates which are no longer susceptible to antibiotic treatment, recent emphasis has been placed on finding alternative modes of treatment of wound infections.
In late BSI, an increased prevalence of resistant bacteria (methicillin-resistant Staphylococcus aureus [MRSA], carbapenem-resistant Klebsiella pneumoniae [CRKP], imipenem-resistant Pseudomonas aeruginosa [PSE-IMP]) and Candida spp. were observed.
However, although the proportion was higher, the prevalence of resistant parasitaemia in children who had received IPTc was lower than that in control children because of the effect of IPTc in reducing the overall prevalence of parasitaemia in these children.
Overall prevalence of resistant hypertension was 8.8% (N = 107/1217).
