Therapy decisions in empiric antibiotic therapy are educated guesses based on the relative prevalence of the microbes causing the infection and the resistance rates of these microbes.
The theoretic risk of antibiotic failure depends on two factors; the prevalence of the microbes in the patient population and the resistance rate of these microbes to the chosen antibiotic [ 24].
However, their cryptic nature has limited recognition of the prevalence of such microbes such that in vitro plant cultures have historically been perceived axenic until proven otherwise.
The infants had a high prevalence of cariogenic microbes and of Fusosbacterium nucleatum and Aggregatibacter actinomycetemcomitans.
Prevalence of various microbes were; G.vaginalis (2%), Candida sp (16%), anaerobic GNB (12%), anaerobic GPB (9%) and Mycoplasmas (8%).
The examined groups of infants had a high prevalence of cariogenic microbes (S. mutans, Lactobacillus species and Actinomyces species) and of F. nucleatum and Aggregatibacter actinomycetemcomitans.
Some authors [ 25- 27] have detected periodontal pathogens in young children, although the prevalence of these microbes has been relatively low.
At 12 months of age, 37% of infants harbored S. mutans, and there was a higher prevalence of these microbes in full-term infants than in pre-term infants, although this difference was not statistically significant.
In general, bacterial sepsis is probably undertreated in tropical countries for several reasons, including unspecific diagnosis of fever, high prevalence of multi-resistant microbes, lack of blood culture facilities, and widespread use of counterfeit drugs.
Here, we report the prevalence, diversity and abundance of microbes in amniotic fluid during preterm labor, and their clinical significance.
