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To determine the prevalence of additional injuries or bleeding disorders in a large population of young infants evaluated for abuse because of apparently isolated bruising.
Given the high prevalence of additional antibiotic treatment, we also examined the pattern of antibiotic use.
The low odds ratio when comparing the prevalence of additional AS cases in AS positive flocks with the prevalence of additional CS cases in CS positive flocks illustrates the lower frequency of AS aggregation in positive flocks compared with CS.
Age at onset and the prevalence of additional Wolfram syndrome symptoms in our patient cohort are reported in Table 2.
For a selection of 10 specific diseases we also present a detailed picture of the comorbidity, i.e. the type and prevalence of additional diseases among that specific disease.
We did not detect any significant difference in prevalence of additional AS in positive flocks related to the type of control measure applied.
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The prevalences of additional AS cases in AS positive flocks were significantly lower than the prevalences of additional CS cases in CS positive flocks (results of the GLMM: OR = 0.03, CI95%: 0.02 - 0.05).
Ireland was excluded from the estimation of prevalences of additional AS cases because AS cases were diagnosed using different diagnostic procedures than the other countries: thorough confirmatory diagnostic procedures instead of rapid screening testing.
The prevalences of additional AS cases in AS positive flocks were not significantly different from prevalences of AS in healthy slaughter (figure 1, Odds ratio (Dersimonian and Laird random effects method, ORDL = 1.07, 95% confidence limits (CI95%): 0.70-1.63) or in fallen stock (figure 2, ORDL = 0.78, CI95%: 0.51-1.20).
When extending the time frame, the costs per infection averted decrease (figure 5), because the declining prevalence of each additional year is compared to the higher baseline prevalence.
The prevalence of ten additional pathogenic parasite species identified with microscopy was, at most, 0.5%.
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