Among continents, Europe/Australia was the most different from Asia, with a prevalence difference of −0.180.
By detection method, estimates for L1 serology were the most different from PCR, with a prevalence difference of 0.112 higher than the intercept.
The prevalence difference in these two Brazilian communities is affected by different definitions, as well as ethnic and economic differences between the two cities.
Studies conducted prior to 1990 were the most different from studies conducted from 2000 to present, with a prevalence difference of −0.282.
They explain the large prevalence difference with the available literature by including more prospective trials (50%% half of which randomised trials) that lack the confounder of patient selection of retrospective trials.
The large prevalence difference as compared to our results and the one reported in literature may be caused by a higher number of prospective trials (50%) of all languages and a statistical correction for low volume studies.
The prevalence difference in infection was similar regardless of BCG vaccination status.
The age-specific prevalence difference ranged from 45.5 to 53.9% across the age groups but did not differ among age groups (test for linear trend, P = 0.91).
The prevalence difference estimates the additional risk for latent infection associated with living in a house of an infectious index case.
Under the 1.25 CEU-YRI disease prevalence difference condition, both the 52 and 93 SNP panels performed well in terms of type I error and estimated OR.
