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Although prevailing evidences suggest that APOE e4 is involved in amyloid-beta aggregation and clearance, we cannot rule out other mechanisms such as neuro-inflammation which is also supported by the newly emerged CR1 locus and CLU with a well-established role in inflammation.
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Hence the prevailing evidence suggests that 5-fluorouracil therapy should not be given to patients with MSI colorectal cancer.
Prevailing evidence suggests that age per se should not be considered as a risk factor for poor adherence [ 2].
But, despite all prevailing evidence to the contrary, mental illness is still the scapegoat of choice.
There is prevailing evidence implicating both neurexins and neuroligins as primary factors in neuropsychiatric disorders [ 3- 11].
Although magic bullets are lacking among the prevailing implementation strategies, evidence suggests that implementation strategies which are systematically tailored to the actual and perceived barriers and facilitators for change increase the success of implementation [ 8, 9].
Pollen data, along with archaeobotanical evidence, suggest a prevailing arable farming economy, vocated to Vitis and cereals exploitation, during the Nuragic phase until 2400 cal BP, replaced since then by a prevailing stock rearing economy.
Thus the prevailing body of evidence suggests that excess iron is a contributing factor for the progression of steatosis to NASH, liver cirrhosis in adults, but these aspects have not been examined sufficiently in pediatric cohorts.
But scraps of evidence suggest otherwise.
The spots of red in the prevailing grayness suggest both hope and menace.
In conclusion, it would appear that the balance of evidence suggests that DMDs for patients with MS are not cost-effective when measured against prevailing cost/QALY thresholds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com