Sentence examples for pretreated population from inspiring English sources

Docetaxel plus vinorelbeine is a promising combination in this heavily pretreated population with 60% responses, even in patients pretreated with paclitaxel.

While the clinical responses in this trial are modest, this treatment was undertaken in a very heavily pretreated population.

This was a more heavily pretreated population than ours.

The rate of 30% was considered clinically relevant taking into account the heavily pretreated population.

In this heavily pretreated population with prior exposure to taxane therapy, half experienced reversible sensory neuropathy.

In this heavily pretreated population, the 6-month progression-free survival was 18%.

Dose escalation trials in pretreated populations of MM patients proved promising, but with higher rates of severe AEs reported in the carfilzomib study.

Both I-tositumomab Y-ibritumomab tiutexan have been extensively studied, and demonstrated high response rates and durable remissions within heavily pretreated populations, with predictable and manageable toxicity.

Initial phase II studies [ 3, 4] demonstrated that the HER1 tyrosine kinase inhibitor (TKI) gefitinib did not have high efficacy in heavily pretreated populations of patients with metastatic breast cancer, particularly after chemotherapy.

In our 5-FU-pretreated population, the overall percentage of patients switching from an I- to an O-based regimen was 45% in both 2002 and 2003.

The present study evaluates the clinical benefit of PLD in an anthracycline-pretreated population and attempts to identify the patients who are more likely to benefit from the treatment.