Exact(26)
Recommended doses were 700 mg m−2 for the heavily pretreated group and 800 mg m−2 for the lightly pretreated group.
The treatment-related mortality was low at 3% in this heavily pretreated group.
Severe, hemorrhagic, and longitudinal ulcerations were developed in H2-RA pretreated group, whereas mildly scattered erosions were observed in antioxidant-pretreated group.
The temporal increase of the 5-HT levels at 20 40 min following galanin administration in the M35 pretreated group could be explained by an increased sensitivity to the acute stress caused during the insertion of the i.c.v.
Interestingly, the simvastatin pretreated group also demonstrated a reduction in MMPs and tumor necrosis factor α concentrations in the BALF.
The good tolerability of irinotecan in this heavily pretreated group of patients was, however, remarkable.
Similar(34)
Pretreatment of both HQH and Dex reduced the cisplatin-induced apoptosis; however, there was no difference between the HQH-pretreated group and the Dex-pretreated group.
A single nephrotoxic dose of cisplatin (20 mg/kg; Nanjing Pharmaceutical Co). was administered via intraperitoneal injection (ip) to the HQH-pretreated group and one NS-pretreated group on the third day 30 minutes before the pretreatment.
A single nephrotoxic dose of FA (150 mg/kg; SIGMA; dissolved by 150 mM NaHCO3) was administered ip to the HQH-pretreated group and one NS-pretreated group per day 30 minutes after the gavage.
A single dose of NS (0.015 ml/g) was administered ip to one NS-pretreated group as a control.
A single dose of NaHCO3 (150 mM, 0.2 ml) was administered ip to one NS-pretreated group as a control.
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