Sentence examples for presumed defects from inspiring English sources

The former can induce defecation or modify stool consistency to make defecation easier, while the latter targets presumed defects in colonic neuromuscular function [ 5, 6].

While these defects were previously ascribed to presumed defects in solute transport (12), the finding here that SLC4A11 moves water across membrane in response to osmotic gradients also explains the defects in kidney and inner ear.

Review articles published a over decade ago described a molecular dichotomy between adults and children (Leonard & Schapira, 2000a, b), with mtDNA defects typically presenting in adult life, and children typically having autosomal recessive disorders due to presumed defects of the nuclear DNA.

In cognitive therapy, patients gradually learn to reorder their thinking, expose their "defect" to others and view themselves more realistically as whole individuals rather than seeing only the presumed defect.

Even if the treatments modify one presumed defect, the person is likely to come up with another, and another, and another, leading to a vicious cycle of costly and often deforming as well as ineffective remedies.

In part, the metabolic impairments of rapamycin are thought to be due to inhibition of mTORC2 rather than mTORC1 [ 45]; while we previously showed that this rapamycin dose was sufficient to inhibit mTORC1 [ 29], it may not be sufficient to inhibit mTORC2 signaling in the marmoset and thus minimize the presumed metabolic defects of rapamycin treatment.

In this case, the mtp5 mutation may modify subcellular metal concentration(s) adequately to compensate for the presumed transport defect in iar1 seedlings, but not alter levels enough to cause toxic metal accumulation that would increase sensitivity to exogenous metals.

We presumed that those defects are located close to each other and mostly are at the NW surfaces (skin effect), and after UHV treatment, reduction in magnetism indicates the decrease in the number of density defects as those in ultrathin films [63].

Thus, transgenic expression of Map3k4 is presumed to rescue defects in this signalling pathway in XY T hp/+ gonads.

Osteogenesis imperfecta (OI) comprises a heterogeneous group of disorders characterized by susceptibility to bone fractures with severity that ranges from death in the perinatal period to subtle increase in fracture frequency and in almost all cases presumed or proven defects in type I (pro collagen biosynthesis.

The main focus of this study is on the identification of the presumed causative genetic defect by a positional cloning approach in combination with whole-genome sequencing of an affected dog.