In a few clones (<10%), the acentric Z had fused with another chromosome and presumably segregated under control of that endogenous centromere.
This hypothesis is also supported by the generated networks in our pathway analysis (Figure 2B), in which NFκB (presumably under the control of TGFβ) is assigned to elicit Ras, PI3K, and MAPK signaling towards actin-mediated responses driving cellular migration, EMT, invasion, and metastasis [59].
Flies (Diptera) provide an excellent opportunity to address this question firstly because the BMP signaling pathway of Drosophila melanogaster has been studied in great detail [ 5, 6], and secondly because tissue specification presumably under the control of BMP signaling along the DV axis of dipterans has undergone significant change [ 7].
On the basis of these various observations, we conclude that MSF and Gel-BD are functionally equivalent, but produced by distinct mechanisms, presumably under independent control (i.e. Gel-BD is a matrikine that is generated by the proteolytic degradation of matrix fibronectin, whereas MSF is the first genetically truncated isoform of fibronectin identified).
We note that the nine physical characteristics of the subjects, presumably under less control of the provider than either laboratory results or even process measures, have a median ICC of 0.017 IQR 0.0111, 0.028) and are significantly different than the laboratory measures (P = 0.034).
Somewhat surprisingly, although there was a trend for a gradual increase in presumably postsynaptic structures under control conditions, we did not observe any significant changes in those structures during potentiation.
Some clusters reflect the processing of a number of miRNAs from a single large polycistronic transcript such that presumably all of the miRNAs are under control of the same promoter and in the same transcriptional orientation [27].
The latter two EST libraries were both obtained from cultures grown only under control conditions, and hence presumably do not reflect stress, cell cycle or different culture stage effects on gene expression.
This indicates that genes that respond to fasting, presumably through nutritional cues, and those gender-predominant genes that are under control of growth hormone substantially contribute to variability in a liver gene expression profile.
Presumably it also wanted to be able to say it had the spill under control.
