Typically, this involves replacing presumably error-free laboratory salinity measurements with indirect measurements that are however affected by various source of uncertainties, and these uncertainties need to be accounted for in order to avoid compromising the quality of the final results.
After Steps (1 - 5), we have constructed the set of solid k-mers that are presumably error-free.
The absence of a homologous repair template in haploid cells in G1 might lead to more (presumably error-prone) repair through non-homologous end-joining (NHEJ).
Patients were also excluded if they did not have prescription coverage in the pre- and post periods, or the index prescription was coded with a days supply of 0 or of more than 180 days, presumably in error.
The low number of reliably detected SNPs and small indels was not the result of insufficient coverage or lack of sequencing quality because we detected 1193 variants present in all sequenced samples that presumably represent errors in the reference sequence.
For instance, the Markov chain approach did not benefit the analysis of data from the normal group as much as the analysis of the mild cognitive impairment or Alzheimer's disease group, presumably because errors in assessing the small volume changes in normal subjects were random and dominated systematic biological changes.
An increased mutation rate in haploids could result from the absence of a homologous repair template in haploid (G1) cells that might lead to increased repair through the presumably more error-prone pathway of non-homologous end-joining (Gorbunova and Levy, 1997; Mao et al., 2008).
This is problematic, as any successful account of the restriction of overgeneralization errors will presumably encompass overgeneralization errors of all types.
Absolute values greater than one (approximately 1% of the remaining probes) were excluded from further analysis as they do not make biological sense and presumably represent measurement error.
The 6,269 contigs that match a query (i.e. exactly or partially match another contig) can only be assembly error, presumably cases where initially different contigs are built up using different reads with the same sequence, leading to the contigs independently converging to the same sequence.
