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The aim of the paper is to bring a new point of view on the purposes of the concurrent engineering and to extend them to market pressures for diversity, shorter product life and competition.
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Selective pressures for increasing diversity at antigenic loci can maintain sequence morphs from common ancestral species that would normally be lost after speciation.
Alternatively, D. virilis and D. melanogaster differ at a number of ecological traits, any of which could potentially lead to different selective pressures for the diversity of AMPs produced: D. melanogaster is tropical, D. virilis is Holarctic; D. melanogaster breeds on a wide range of substrates, typically rotting fruit, D. virilis breeds on sap fluxes [ 20].
The pressure for functional diversity on tick Kunitz peptides may be that several targets have been associated with their inhibitory activity such as trypsin, elastase, kallikrein [ 70], chymotrypsin [ 71], tissue factor complex inhibitor [ 38] and ion channels [ 40].
These results may also arise from the persistence of Asian-like lineages in North American water birds following initial introduction events or vice versa (e.g., our N1 results) and suggest selective pressures for maintaining genetic diversity in the NA surface glycoprotein to evade host immunity (Dugan et al. 2008).
More to the point, respect for diversity under pressure.
A positive selection pressure for the V3 diversity can be the humoral immunity.
Due to the limited antibody repertoire encoded by the quasi-monoclonal mice, selective pressure for Ig gene diversity is high, causing both hypermutation and frequent V gene replacements [30].
"For Diversity.
I hunger for diversity".
Another strike for diversity?
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