Interestingly, GRβ geo /+ mice failed to show the full extent of the HPA and blood pressure adaptions to the HF diet seen in control mice, suggesting that tissue GR density limits the adaptive response to chronic dietary stress.
Like propagule pressure, pre-adaption is not a necessary precondition for successful invasion, because climatic niche shifts have been reported for invasive species.
It will be of great interest to determine whether GR density influences the prenatal programming effects of glucocorticoids in the same way that it alters the postnatal blood pressure and HPA adaptions to a chronic HF diet.
Our results indicated that mobile genetic element-imposed selective pressure led to genome adaption to the strain by trimming nonessential genes and pathways during cultivation in the laboratory.
Few of the obviously complex mechanisms of bacterial adaption to pressure are analyzed on molecular level, usually for model organisms like lactic acid bacteria.
Huss JM, Imahashi K-I, Dufour C, Weinheimer CJ, Courtois M, Kovacs A, et al. The nuclear receptor ERRα is required for the bioenergetic and functional adaption to cardiac pressure overload.
However, whereas a high-fat diet caused HPA activation and increased blood pressure in control mice, these adaptions were attenuated or abolished in GRβ geo /+ mice.
Nevertheless, reports on different adaption due to environmental pressure within the Hanwoo varieties are sparse and do not allow for an in depth interpretation.
Genes with significant positive selection may play key roles in bacterial adaption to different environmental pressures.
Artificially selected populations can be subjected to much stronger selection pressures than natural populations, thus their adaption to a new experimental environment can be considered to be a process of accelerated evolution.
