Sentence examples for preserving stem cells from inspiring English sources

In this review, the importance of preserving stem cells during in vitro expansion and controlling cell differentiation as well as tissue organization to ensure quality and functionality of tissue-engineered organs will be discussed, while focusing on skin and cornea.

"Bivalent domains" are pivotal chromatin structures composed of both repressive (H3K27 methylation) and activating (H3K4 methylation) marks that silence developmental genes while preserving stem cells' ability to be activated in response to appropriate developmental cues.

Cells were expanded (225-fold within 10 days) on nanofiber matrices preserving stem cell phenotype [26].

This study implicates Notch signalling as a key pathway for preserving stem cell function in dystrophic muscles, and suggests that this pathway might be modulated to improve long-term satellite regenerative function in DMD.

Serious cardiac side effects can result from the chemical used to preserve stem cells, making the transplant risky if a patient is unstable.

In contrast, the klotho protein was shown to suppress Wnt-signaling transduction, and inhibit cell senescence and preserve stem cells.

For these reasons, ALDH is considered a protecting or detoxifying enzyme, able to preserve stem cells from cytotoxic effects [ 2- 4].

Minimal cytokine stimulation of HSCs may help preserve stem cell function and provide for the effective "activation" of stem cells that renders them susceptible to transduction.

On the other hand, all these data show the need to develop novel culture protocols able to preserve stem cell plasticity.

Maintenance of the genome appears to be of utmost importance to preserve stem cell function and to reduce the risk of ageing associated dysfunctions and pathologies.

In conclusion, results provided by the present study suggest the need to develop novel culture protocols able to preserve stem cell plasticity.