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In its resting state, the usher TP is gated closed by the PD, preserving integrity of the OM.
Altogether, this preliminary evidence suggests that, during ischemia/reperfusion, INaL inhibition may be more effective in preserving integrity of mitochondria than in improving their function.
Thus, the regulation of these genes by Snai2 in response to DNA damage could be important in preserving integrity of tumour target cells and supports the view that failure to control Snai2 expression can produce cancer and alterations in development (Perez-Mancera et al, 2005; Perez-Mancera et al, 2006).
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The use of antioxidant therapies may help to preserve integrity of glycocalyx.
In the control group, there was well preserved integrity of mitochondria without cellular edema.
The Bax/Bak oligomerization is directly antagonized by antiapoptotic Bcl-2 members, which preserve integrity of the mitochondrial membranes [ 29, 30].
IMPACT: Our findings suggest that SIRT1 may be a therapeutic target to foster MSC differentiation to preserve integrity of MSC-derived tissues in aging animals.
Czarnocka et al (2001) used a TPO capture method that has the advantage to preserve integrity of the antigen structure and thereby allows immunological detection.
To preserve integrity of the aortic valve region, the entire heart of each animal was sectioned from its apex to the source of the coronary arteries, close to the point of greatest occlusion by plaque.
It is assumed that cancer possesses an important function of altruistic nature: as a mediator of negative selection, it serves to preserve integrity of species gene pool and to mediate its evolutionary adjustment.
Their studies have shown that statins and PPAR agonists stabilize myocardial and microvascular function, preserve integrity of pulmonary endothelial cell tight junctions and prevent pulmonary edema, and promote resolution of acute inflammation (13, 14 ).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com