To preserve a familywise type I error of 0.05, in accordance with Bonferroni principle a difference was regarded as statistically significant if P < 0.05/19 = 0.00263.
Since such strong OD shifts and reductions in closed eye responses are usually only observed in juvenile, critical period mice (Espinosa and Stryker 2012), our findings suggest that adult rl−/− mice preserved a juvenile type of OD plasticity into late adulthood.
The results of this study emphasise the roles of landscape composition and configuration as ecological filters and the importance of preserving a range of landscape types to maintain functional biodiversity at regional scales.
A trial with 286 children per arm has over 80% power to detect a halving in the frequency of adverse events, using a significance of 0.025 (to preserve an overall type 1 error rate of 5% for the primary endpoint when there are 2 comparisons, each alternative drug group to be compared with SP plus/ AQ).
Up to 5 formal interim analyses are planned, at time points to be determined by the Safety and Data Monitoring Committee, with a stringent nominal significance level (3 standard deviations; 2 P = 0.003) to preserve an overall type 1 error probability of no more than 0.05.
Old Hittite, the written embodiment of the earliest Indo-European language that has been discovered so far, is known from some tablets preserved in a type of handwriting ("old ductus"; see epigraphy) that was typical of the Old Kingdom period (c. 1650 c. 1500 bce).
In this way, we can move from a fixed-size vector type of encoding to a variable length sequence type encoding while still preserving a high discriminative power.
Preserving an overall two-sided Type 1 error rate of.05, Lan-DeMets [ 40] group sequential methods with the most conservative alpha spending function (O'Brien-Fleming) were used to reject the null hypothesis (efficacy boundary, if large treatment differences appear before the end of the study).
His attorney general has praised the Immigration Act of 1924, a law crafted by eugenicists and championed by people hoping to preserve a "distinct American type".
The Bonferroni Holm method was used to preserve a family-wise type I error rate of 0.05.
