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Duzel, E., Schutze, H., Yonelinas, A. P. & Heinze, H. J. Functional phenotyping of successful aging in long-term memory: preserved performance in the absence of neural compensation.
This enhancement of contralateral PMd is accompanied by preserved performance in a stimulus-response matching task.
This enhancement of contralateral PMd is accompanied by preserved performance in a conditional action selection task.
Thus, activation of the lateral premotor loop may constitute a dynamic, compensatory mechanism due to dopaminergic withdrawal accounting for preserved performance in externally cued tasks as frequently observed in clinical practice.
Indeed, prefrontal patients may demonstrate preserved performance in tasks where switches are cued, but impaired performance when the switches have to be self-generated (Burgess, 2000; Shallice and Burgess, 1991).
MCI subjects fulfilled the Petersen's diagnostic criteria [ 15], including subjective memory complaints, normal general cognition, preserved performance in activities of daily living, absence of dementia and a measurable impairment in memory function, with or without deficit in other cognitive domains [ 16].
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61 However, only the subgroup with a high level of cardiovascular fitness, measured at follow-up, was able to preserve performance in episodic memory recognition, while the low-fit subgroup deteriorated from postintervention to 1-year follow-up.
This research has shown that effective reorganization resulting in preserved performance is underpinned by increases either in right-hemisphere activity (Weiller et al., 1994; Buckner et al., 1996; Blasi et al., 2002; Leff et al., 2002; Fernandez et al., 2004; Winhuisen et al., 2005; Voets et al., 2006) or by perilesional activity in the left-hemisphere (Breier et al., 2004).
In sleep-deprived persons, availability of a neutral or valid cue has been shown to afford preserved performance whereas invalid cues result in delayed responses.
A compensatory cerebral response appeared to be elicited during sleep restriction [ 11] that may have helped focus attention and suppressed extraneous mental processes [ 5], resulting in relatively preserved performance.
In addition, they recruit a RH frontotemporal network that works in conjunction with the LH network to support preserved performance.
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