Sentence examples for preserved mitochondrial function from inspiring English sources

Flow cytometry revealed significantly higher mitochondrial membrane potentials in the treated subjects, suggesting preserved mitochondrial function.

Hypothermic preconditioning preserved mitochondrial function by delaying the pathological opening of the mitochondrial permeability transition pore (mPTP), whereas transient mPTP flickering remained unaltered.

While these findings were obtained without induction of hypothermia, preserved mitochondrial function documented by an increased complex I and complex II efficiency assumed major importance for the H2S-induced cytoprotection [ 10].

They found evidence of mitochondrial fragmentation (smaller spherical mitochondria), preserved mitochondrial function, resistance to oxidative stress in terms of mitochondrial membrane depolarization and cell viability, and reduced sensitivity to MPTP opening.

An analysis of Mitochondrial Membrane Potential (MMP) made with the potentiometric dye TMRM also indicated that EGFP-p53R-positive cells are less susceptible to undergo MMP decrease with respect to those positive for EGFP-p53P, suggesting that these cells have a better preserved mitochondrial function.

mTOR expression is therefore not restricted to tumours with preserved mitochondrial function but is also present in pseudohypoxic PCC/PGL, therefore suggesting cross-talk between the two pathways.

The methylene violet analogues were evaluated for their ability to preserve mitochondrial function in Friedreich's ataxia (FRDA) lymphocytes.

We find that mild muscle mitochondrial distress preserves mitochondrial function, impedes the age-dependent deterioration of muscle function and architecture, and prolongs lifespan.

Hydrogen sulfide (H2S) is well known to protect the heart from ischemia reperfusion injury by specifically modulating the mitochondrial adenosine-triphosphate-linked potassium channel, thereby preserving mitochondrial function.

This study suggests that very low concentrations of mitochondrial-targeted H2S (sub nM) induce positive bioenergetic effects, preserve mitochondrial function and cell integrity.

Selected pyridinol analogues of the experimental neuroprotective drug idebenone have been synthesized and evaluated as antioxidants capable of preserving mitochondrial function.