Sentence examples for preserved interaction with from inspiring English sources

Two representative Type 2B mutant pVHL proteins partially preserved interaction with VBC complex members despite reduced binding to Elongin C, and the Type 2B mutant R167Q pVHL retained wild-type levels of ubiquitin ligase activity towards its target HIF-1α HIF-1αro.

The observed discrepancy between the defective nuclear targeting of DISC1-37W and its largely preserved interaction with ATF4 prompted us to analyse the sub-cellular distribution of the two proteins in co-transfected cells.

The in situ approach we have used allows the analysis of mitochondrial function within an integrated cellular system, preserving interactions with other cell components that are important for metabolic channelling and intracellular energy transfer [ 37– 37].

Measurements show preserved interactions consistent with those observed for AS-605240 in the PI3Kγ X-ray structure.

Membrane proteins isolated from VF12 strains were solubilized prior to gel-filtration chromatography using either non-denaturing detergent perfluorooctanoate (PFO), which preserves interactions within protein oligomers [23], [24], or with SDS, a strong ionic detergent which disrupts protein interactions [25].

Indeed, this approach preserves interactions between cells present in the correct ratios, with physiological organization of the epidermal 3D-structure supported by the dermis.

The condition follows from the assumption that light is emitted and absorbed by atoms independently, and that the thermal equilibrium is preserved by interaction with atoms.

This mutant protein preserved its interaction with integrin β1 that could be sufficient to support ES cell proliferation and early embryogenesis.

Both the ectodomain and the TMS of US3 are essential in order to preserve the interaction with MHC I. Notably, two forms of US3 have been observed.

A symmetry-related molecule (in an equivalent position to that forming the first interaction described for molecule A) preserves the interaction with Tyr112.1 and Tyr113 on one side, although the side chain for Tyr108 is disordered, and the position of backbone atoms for residues 112.2 and 112.1 is shifted by ˜2Å.

Moreover, these hPS molecules preserved their interactions with the corresponding CT residues during all the remaining simulation time.