Sentence examples for preserved circulating from inspiring English sources

Exact(6)

The pharmacokinetics of Zr-rituximab confirmed the fast clearance of Zr-rituximab from the blood in both patients (particularly patient 1) with preserved circulating CD20+ lymphocytes without preload and the significantly slower clearance of the radioconjugate (comparable with the clearance in patients with B-cell depletion) with a preload (Fig.  10).

Without a preload, an increase in whole-body dose of 59%and87%87 % was noted in two patients with preserved circulating CD20+ B cells.

In the two patients with preserved circulating CD20+ lymphocytes, three lesions showed less or no uptake without a preload, while other lesions showed higher uptake.

In contrast, in the two patients with preserved circulating CD20+ lymphocytes, the preload of unlabelled rituximab cleared circulating B lymphocytes from the blood, reduced whole-body radiation dose, significantly reduced radioactivity uptake in the spleen, and resulted in slower clearance of the radioconjugate from the circulation.

In contrast, it had a variable influence on tumour targeting in the two patients with preserved circulating CD20+ lymphocytes, enhancing uptake in three lesions (of which two were visceral) by improving biodistribution and preventing sequestration of the radioconjugate by the antigen sink, while impairing targeting of other tumour sites due to partial saturation with unlabelled rituximab.

In the five patients in this study a preload of rituximab improved the biodistribution of the radioconjugate by preventing its sequestration in patients with preserved circulating CD20+ lymphocytes, but consistently impaired radioconjugate tumour targeting in patients with B-cell depletion, the latter representing the majority of patients eligible for RIT in the "rituximab era".

Similar(54)

However, the majority of cell stabilizing reagents have not been formally tested for their ability to preserve circulating plasma tumor DNA.

The rumors keep circulating.

A cell transportation solution that preserves live circulating tumor cells in patient blood samples.

Hand sellers are preserving and circulating this new alchemical trade wisdom in online forums on sites like BookThink and AbeBooks.

It lowers DPP-4 activity in a sustained manner following once daily administration, preserves the circulating levels of intact GIP and GLP1 following meals in both acute and chronic studies and reduces blood glucose levels without significant increases in hypoglycemia [ 84].

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