Exact(7)
Finally, extensive Pin1 WW mutation work by Kelly and co-workers (24) suggested that an I28A substitution would preserve overall folding.
All systems were solvated with explicit TIP3P water molecules and Na+ and Cl-counterions were added as background salt and to preserve overall electrical neutrality.
Clades 3 and 6 independently acquired somewhat similar changes, supporting the idea that changes within the PARP catalytic domain may be constrained in order to preserve overall structure.
However, RCR values did not differ significantly between ages, indicating that these changes are perhaps adaptive to preserve overall mitochondrial function, as any changes in OXPHOS will alter RCR values [ 50].
Also DAPI staining is relatively easy to perform that protein-based IHC since protein is more sensitive than DNA to pre-analytical variables, particularly when the motive is to preserve overall DNA structure rather than specific base pairs.
Our data suggests that losses in cellular mitochondrial function as a consequence of MAO-B induction may be at least in part due to effects on oxidative effects on parkin activity that impact on its ability to remove damaged mitochondria and preserve overall cellular metabolic function.
Similar(53)
With continued updates and refinement, our API will support most scenarios in a way that preserves overall system performance.
"I think it's right that the House of Commons preserves overall the right to vote on all matters that affect any part of the United Kingdom within the House of Commons.
On the other hand, recent experimental studies on disc cells have demonstrated an important role for the nucleus pulposus in preserving overall disc structure.
We hypothesized that cell ingress could be expedited in scaffolds by increasing porosity, while at the same time preserving overall scaffold anisotropy.
In Earth, the third of the series, although there seems to be more potassium present at around 11‒12 wt% oxide, it is not better preserved overall; the results reported are for one particle of smalt that retains its colour because it is large, chosen for analysis because it is more representative of the original composition of the smalt than the deteriorated particles.
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