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Its soft tissue doesn't preserve in human fossils, but its lower position in our necks affects the shape of the base of our skulls.
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One of them is preserved in human, mouse and dog, whereas the remaining one is preserved only in human and mouse.
In total, we find that five brain modules were strongly preserved in human blood.
Although the differential expression of TNMD seen in bovine samples between NP and AF cells was preserved in human samples (P < 0.05), the fold change was lower (approximately 100-fold in bovine, and approximately 5-fold in human).
XCI is stable and well preserved in human lymphoblastoid cells (Johnston et al., 2008, Zhang et al., 2013) that provide convenient resources to study XCI effects in human diseases (Amir et al., 2000).
Different groups have shown that the metabolic capacity is better preserved in (human) liver slices (Elferink et al. 2011; Olinga et al. 1997; Martin et al. 2002) compared to (human) hepatocytes.
However, it is not clear whether this function is preserved in humans.
Furthermore, our studies in human systems using IHC and expression profiling data validate that such lineage restriction is highly preserved in humans as well.
β-Cell mass is well preserved in humans with advanced aging.
Furthermore, humans with loss-of-function mutations in leptin and its receptor have normal BP despite severe obesity, suggesting that these mechanisms are likely to be preserved in humans.
Further investigation will be necessary to unveil the relevance of astroglial function and eventually brain development, but the differential expression of OATP1C1 appears to be a rather general difference that is even preserved in humans.
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