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These mRNAs could then be delivered to P-bodies for degradation or storage in order to preserve a pool of transcripts whose translation is rate-limited for cell growth [ 55].
It is also possible that under ubiquitin-depletion stress, atypical NEDDylation serves as a generalized response to preserve a pool of free ubiquitin by terminating or slowing ubiquitin chain elongation on substrates.
These results suggest that Id1 is required in early hematopoietic stem cells to restrain the commitment to the myeloid lineage and preserve a pool of cells that give rise to endothelial progenitors in response to vasculogenic growth signals.
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It's time to finish the job and to return Fannie and Freddie to their mission of preserving a pool of capital available so people from all walks of life can access homeownership and contribute to the economic benefits that accompany it. .
An upregulation of Notch-1 is critical in the signalling pathway that preserves a pool of undifferentiated progenitor cells [ 65, 66].
This preserves a pool of progenitors and, at the same time, maintains high levels of Hes5 expression, that in turn directly inhibit the oligodendrocyte generation during the neurogenic phase.
This would necessitate depleting the expanded pool of autoreactive T lymphocytes and B lymphocytes, retarding the process of immune senescence in the residual lymphocyte populations, restoring the integrity of regulatory networks, and, at the same time, preserving a pool of memory cells capable of responding to environmental pathogens.
Tuesday's report rejects Labour's traditional line that Trident should be kept as a "general insurance against an uncertain future" (to quote Tony Blair) or to maintain the UK's status, or that it is needed to preserve a valuable pool of skilled naval engineers.
Mr. Ickes says the campaign can preserve a large enough pool of holdouts for her to rally before the Denver convention.
Teeters' Taxidermy Studio of Halifax, Pennsylvania stuffed and costumed this hog-loving squirrel, alongside a preserved pool shark, a squirrel in full KISS garb, and two Jedi squirrels with dueling lightsabers.
Al Calderin, who grew up in Williamsburg and wants to preserve the pool building, remembers paying 10 cents to get into McCarren.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com