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In our approach, there is a novel option to employ only sequence information to score the preservation of functionally important residues.
To assess whether the distribution of introns in essential and nonessential genes (fig. 5) might be driven by this neutral process rather than reflecting the preservation of functionally important introns, we used logistic regression to model the presence/absence of introns using genic characteristics as linear predictors (see Materials and Methods).
It has been hotly debated that protein structural constraints because of protein-protein interaction could introduce a slow evolutionary rate in AA sequences of the contacting regions of both proteins, because of the necessity of the preservation of functionally significant structures and of the parallel evolution between the paired interacting regions [ 53- 55].
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The second strategic advantage of recalcitrant seeds is the preservation of intact functionally active vacuoles.
Fuzzy functional template-based objective methods, encoded in our structure-based scoring scheme, provide a clear representation of the extent of spatial preservation of known functionally important residues.
It is the number and preservation of those truly functionally redundant reactions that are of particular interest and are the subject of our study.
It is likely that for preservation of the repressed state either multivalent deposition of functionally related epigenetic marks or longer-lasting trigger stimuli are necessary.
The preservation of IL10 gene paralogs and other functionally related genes is likely the result of co-evolution, through which they act optimally in concert to confer biological effects, specifically in the context of infections with agents like HIV-1 where the antigenic repertoire evolves rapidly within the host.
The data might provide a useful basis for the preservation of pronator quadratus muscle applied to a functionally reduced fracture regarding the potential efficacy of conventional volar plate osteosynthesis.
overview of functionally characterized genes in rice online database.
His research interests include thermomechanical properties of functionally graded materials.
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CEO of Professional Science Editing for Scientists @ prosciediting.com