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Septage disposal presents technical difficulties due to its high concentrations of solids and nutrients.
However, targeted dissection of mineralized tissues, dental cementum (DC), alveolar bone (AB), and dentin (DE), presents technical difficulties.
However, growing hepatocytes as individual spheroids is non-representative of their hepatic organization and presents technical difficulties related to controlled growth, for example during the setup of co-cultures with non-parenchymal liver cells.
The examination of ICU or ER patients in loco presents technical difficulties related to the capture of echocardiographic images due to factors specifically related to critically ill patients, such as the use of mechanical ventilation, limited mobility and difficulty in positioning the patient for the examination; these issues were not considered in the above-mentioned studies.
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Large pulmonary arteriovenous malformations (PAVMs) carry a significant risk of neurologic complications and present technical difficulties in transcatheter treatment with use of coils or detachable balloons.
Bending tests involve complex internal stress fields and produce results that are influenced by the testing skill and orientation of the specimen and 3- and 4-point bending tests present technical difficulties associated with sample positioning and the subsequent data analysis with irregular samples such as these.
The half-life of the parent phthalates is very short, and high levels of contamination in laboratories present technical difficulties when analyzing for phthalates (Lorber et al. 2010).
In the field of mathematics, studying the limits of systems of particle systems in interaction has been a long-standing problem and presents many technical difficulties.
This method presents important technical difficulties since the maximum imaging depth achievable in the spleen is severely hampered by the absorption and scattering of light by blood.
Trabeculectomy presents special technical difficulties in childhood because buphthalmic eyes are bigger than usual and the lumbar anatomy is frequently impaired and it can lead to iris and ciliary body incarceration and vitreous loss [ 30– 30].
Measuring foot-to-foot PWV presents some technical difficulties: the quality of the measurement depends, among other factors, on the skills of the operator, the characteristics of the subject, the accessibility of the arterial pulse, and the precision in the measurement of the length of the arterial path and of the transit time.
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