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This paper considers the implications of such approximations in clinical trials in practice and presents sample size for exact α levels based on the exact test.
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The present sample size may seem small for a genetic association study, but was able to confirm the association between rs439401 TT genotype and an adverse profile of metabolic traits only in stressed persons found in our previous study [11].
However, our results contradict the main hypotheses and the present sample size is relatively small.
Boldface: Power > 80% 81: Assumptions used when the present sample size of 2000 was determined.
Nevertheless, the present sample size was sufficient to detect significant within group improvements.
However, results are in contradiction to prior hypotheses and the present sample size is relatively small.
The present sample size may have been small, which is subject to type II errors.
40 With the present sample size calculation, this requirement is met.
However, the present sample size was not that dissimilar to other questionnaire validation studies in South-Asian languages [ 8, 15].
These findings need to be investigated further and cannot be definitively tested given the present sample size.
We first describe the D statistic, and then present sample size calculations based on D for use in prognostic studies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com