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Here, we have studied the antigen presenting capacities of conventional NK cells, IKDCs and cDCs during influenza infection.
We found in vivo and ex vivo evidence for antigen presenting capacities within IKDCs and conventional NK cells during influenza infection.
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Boaden is no stranger to the airwaves as a former host of Radio 4's Woman's Hour, but it is highly unusual for a senior BBC executive – creative director Alan Yentob excepted – to appear in a presenting capacity.
Their amount, phagocytic function, and antigen presenting capacity increase with gestational age (GA) [5, 10].
It is unknown whether GA affects dendritic cells (DCs), which, besides strong antigen presenting capacity, orchestrate Th1 and Th2 responses.
For this reason, it is critical to define the time interval when presenting capacity values and to never compare capacity values that were developed from different time durations.
We discuss the current status of clinical trials and new approaches to exploit the antigen presenting capacity of DC to design vaccines of the future.
We found that similar to migrant Gr-1+ MoDC the CD8αα+ LNDC had modest antigen presenting capacity.
Thus this subpopulation of CD8αα+ DC could have potent antigen presenting capacity like the migrant CD11bhi RDC.
This allowed us to take advantage of the gB-specific T cell receptor transgenic as a tool to probe the antigen presenting capacity of individual subsets of DC.
To study the antigen presenting capacity of the different cell subsets we infected mice either with an influenza virus containing the OVA MHCI (SIINFEKL) or MHCII OVA323 339 epitope.
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