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Indeed, in both OI and NAI, unexplained, multiple and repeated fractures may occur; children may present with bruises and contusions; radiographs may reveal different types of fractures, fractures of various ages that went undetected and no evidence of osteopenia.
Our patient presented with severe bruising at birth, probably due to thrombocytopenia and coagulopathy.
He presented with easy bruising and mild gum bleeding.
He presented with easy bruising, recurrent epistaxis, and bleeding after tooth extractions despite prophylaxis with platelet transfusions.
A previously healthy 7-month-old girl presented with paleness and easy bruising, preceded by croup.
A 6 year old African-American female presented with several weeks of bruising and epistaxis.
Orbital compartment syndrome (OCS) is a clinical diagnosis that should always be suspected in patients presenting with periorbital bruising, impairment of vision, fixed dilated pupils, and proptosis following a blunt trauma [3].
We reviewed the hematologic evaluation of children who presented with symptoms of bleeding and/or bruising suspicious for NAI to determine the frequency of hematologic tests, abnormal hematologic laboratory results, and hematologic diagnoses.
Two years subsequently, he presented with cushingoid features with a moon face, easy bruising, abdominal striae, centripetal fat distribution and marked proximal myopathy.
"If they present with bleeding and/or bruising and they get checked by the pediatrician, and the platelet count is very low, then if the other counts are normal and there's no major finding other than signs of bleeding on exam, then they almost certainly have I.T.P., especially if the bleeding developed recently," he said.
Andrea Contenta, a humanitarian affairs adviser for Doctors Without Borders, says his organization has heard hundreds of reports of such violence on the border and routinely sees migrants presenting with injuries that support their claims: bruising consistent with beatings, dog bites and Taser wounds, inflammation from pepper spray.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com