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Five out of six patients of group 1 and none in group 3 presented grade 1 diarrhoea.
Other associated injuries included one medial meniscal tear treated through partial meniscectomy, while another two patients presented grade II Outerbridge patellar chondropathy and were not treated (Table 1); at time of injury, no patients had any associated fractures.
One patient presented grade 4 leucocytopenia.
One patient presented grade 4 neutropenia and grade 3 asthenia and the other presented grade 3 asthenia and grade 3 constipation with intestinal subocclusion (Table 3).
At 6 months from the end of therapy, 2 patients (3.4%) presented grade 1 GI toxicity and 7 patients (11.9%) presented grade 1 GU toxicity.
The eighteen and nineteen year-old group presented grade 5 of IOTN (very great treatment need).
Similar(43)
Under these conditions the thin SiO2 layers presented graded properties with a denser layer at the Si (100) interface and a hybrid organic inorganic structure at the surface.
Only one patient presented grade-3 drowsiness.
Only studies where conclusions were supported by the evidence presented (grades 3 and above) were considered.
Treatment was well tolerated, with one patient presenting grade 3 neutropenia and grade 3 diarrhoea.
Moreover, high expression of ERα/PI3K was associated with tumour grade, with more tumours presenting grade 2 or 3 when ERα/PI3K was highly expressed (p = 0.014; Table 3).
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