Sentence examples similar to presented a significant difficulty from inspiring English sources

Such annotations, which are clearly a consequence of high-throughput experiments, present a significant difficulty in method evaluation.

This presented a significant obstacle.

Intermediate cases therefore represent a significant difficulty.

These children show greater difficulty regulating these areas, presenting a significant risk for other neuropsychiatric disorders, such as depression and anxiety [ 24, 30- 33].

The difficulty of sampling airway biochemical markers in humans presents a significant challenge to the evaluation of airway status.

Traditionally regarded as Problematica (i.e., of unknown affinity), these bizarre taxa present a significant challenge in terms of often complex preservation, not to mention the difficulties in reconstructing a plausible functional morphology.

The settlements present a significant shift.

The shift presents a significant challenge for overstretched security agencies.

This presents a significant risk for investors.

Starting a carrier presents a significant capital challenge, however.

Fortunately, this crisis also presents a significant opportunity.