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However, the lack of sufficient amino acid sequence data for all but a few of the class 1 antigens presents a major difficulty in the allelic assignment of those DNA clones obtained in man3 5 and mouse6 8.
W. V. O. Quine's indeterminacy thesis of radical translation presents a major difficulty for the explanations of the conceptual content and meaning of terms in Yoruba language provided by the onisegun to Hallen and Sodipo.
Inbreeding depression presents a major difficulty in generating and maintaining highly homogeneous strains.
Packaging presented a major hurdle.
However, it is also found that a major difficulty in the present design is the insufficient damping of the rotational mode, which limits the applicable control gain and achievable performance and should be corrected by proper mechanical redesign in the future.
Lighting is a major difficulty.
It just feels like a major difficulty in life".
This poses a major difficulty for a reliable interpretation of geochemical results.
A major difficulty is the system and computational complexity.
This fact is a major difficulty for DIC.
A major difficulty of denoising is to separate the underlying signal from the noise.
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CEO of Professional Science Editing for Scientists @ prosciediting.com