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Assignment of structures to isoprenoids once presented a challenging problem because the method for determining the structure of an organic compound was based entirely on studies of chemical reactions.
Instead of going through the motions of the usual five-borough shout-out, for example, Ms. Stone presented a challenging audience-response segment: a battle of the sexes played out as a singalong to the Isley Brothers classic "For the Love of You," with extra skills required from the women asked to sing harmonies during the men's lines.
As a result, we presented a challenging hypothesis: the continent was created in the ocean.
The structure of recombinant ValA from S. hygroscopicus 5008 presented a challenging molecular replacement problem, as the most similar known structures were only ∼30% identical in sequence.
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But Hurricane Sandy also presented a challenge.
Even buying a bed presented a challenge.
Installing solar panels along the 49th parallel presented a challenge.
But the day's menu presented a challenge.
To outside linebacker Bryan Thomas, Roethlisberger presented a challenge.
For Devlin, weighing authenticity against current sensibilities presented a challenge.
Diagnosis also presented a challenge among non-specialist healthcare staff.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com