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In DSM-5, the authors stress the importance of differentiating a mental disorder from a culturally approved response to stress or loss and of appreciating culture-specific presentations of symptoms [ 2].
40 Well-designed experimental studies in the UK and the USA have shown how GPs take account of gender, ethnicity and age in assessing the likely importance of symptom presentations: given the same presentations of symptoms of coronary heart disease (CHD), GPs were more likely to attribute these to CHD in men and to have a higher level of certainty about their diagnosis.
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All patients presented with hematuria with the presentation of symptoms occurring anywhere from mid-chemotherapy treatment to as far as 60 days following treatment cessation in patients with chemotherapy-induced cystitis.
This may be relatively unimportant in terms of reducing delay in investigation, as current initiatives are based on expediting the diagnostic process once a symptom has been presented, rather than encouraging earlier presentation of symptoms by patients.
Therefore, early diagnosis of CRC is highly dependent on the interaction between the patient's interpretation and presentation of symptoms and the GP's response to the presented symptoms [ 5].
In the present study, these socio-cultural factors are addressed by understanding the presentation of symptoms in the study population and subsequently evaluating the symptom and treatment response in relation to its genotype.
The average time from presentation of symptoms to diagnosis is 13 years.
For some of our patients, their proximity to hospitals or cultural beliefs mean that they will bypass GPs altogether and attend A&E departments for first presentation of symptoms.
"A physio or doctor treating a player on the pitch simply cannot accurately gauge the severity of the damage caused to the player's brain in such a setting as there may be delayed presentation of symptoms.
However, a thickened mucous membrane can be physiologic or benign without presentation of symptoms.
The use of xenograft models has overcome the obstacle of time delay in the presentation of symptoms, which remains a crucial drawback of genetic models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com