Sentence examples for presentation to specific from inspiring English sources

Antigen processing and subsequent presentation to specific T cells is necessary for effective bacterial immune responses involving both CD4 and CD8 T cells.

It is becoming clear that adaptive immune responses against self-tissues are impacted by miRNAs at several distinct points ranging from initial antigen presentation to specific effector mechanisms that are at the heart of tissue damage during autoimmunity.

In a previous report we showed that glycosylated and non-glycosylated forms of the same CII259 273 epitope were differentially processed in lysosomal compartments for presentation to specific CD4 T cells [ 27].

The involvement of macropinocytosis in uptake of autoantigens, such as CII, by both DCs and macrophages for subsequent antigen processing and presentation to specific T cells is a novel finding.

Consequently, effective anticancer immunity may be achieved by recruiting professional host APC for tumour Ag presentation to promote specific T-cell activation (Miller et al, 2000).

Besides the indirect effects on the survival and function of T cells through autophagic proteins, autophagy also showed a direct role in antigen presentation to antigen-specific T cells (a process essential for the induction of acquired immunity) [41].

One of the most important issues to solve is the efficiency of antigen delivery to dendritic cells in order to achieve an appropriate uptake, processing, and presentation to Ag-specific T cells.

Indeed disulfide bond reduction of proteins facilitates processing and presentation to antigen-specific CD4 T cells [37] [40].

This protective effect may arise from the activity of α-defensins1-3 to damage the virions prior and/or after their internalization by immature DC, and hence favoring a more efficient viral processing and presentation to HIV-specific CD4+ T cells, without or with a minor rate of transmission of infectious HIV-1 virions.

In vitro work in the human immune system illustrated how activated NK cells expressing MHCII and co-stimulatory molecules could process influenza hemaglutinin (HA) protein and virus infected targets for presentation to HA-specific CD8+ and CD4+ T cell clones [20].

Electron microscopy and antigen presentation to CII259 273-specific T and presentation CII259 273-specificonsTrandd that upresentation by both types of APcellepended on actin polymerisation (cytochybridomassensitive) andemonstrateduffling (amiloride-sensithat), suptakeing the principal rofte was maCIIpinocytosis.