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At presentation, the majority of patients complain an asymptomatic mass and slight ulceration.
Although advanced epithelial ovarian cancer is sensitive to platinum-containing chemotherapy at first presentation, the majority of patients experience disease relapse and their management at this stage is often difficult.
At presentation the majority of the patients (85%; 71/84 patients) had fever, 24% (22/92) had headache, 17% (16/92) had vomiting and 4% (4/92) had seizures.
At presentation, the majority of patients, 74 out of 79 (94 %) had primary disease, while 2 out of 793(3 %) had a local recurrence and 3 out of 794(4 %) had metastatic disease.
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As evident from these presentations, the majority of the parameter values are derived from the model versions previously published in Basak et al., 2007 (Cell. 2007 Jan 26 128 2):369-81) and to some extent, from Shih et al., 2009 (Proc Natl Acad Sci U S A. 2009 Jun16;106(24):9619-2) as well as Shih et al., 2012 (Nat Immunol. 2012 Dec;13(12012162012).
Approximately 60% of patients have clinically localised disease at presentation, with the majority undergoing curative nephrectomy.
Because hilar cholangiocarcinomas are often unresectable at presentation, in the majority of cases treatment focuses on palliation of symptoms.
The MELD score is approved for assessing end-stage chronic liver disease and not for acute hepatic dysfunction, which was the presentation of the majority of the patients in our study population.
More than half of the patients are at risk of malnutrition at time of treatment presentation, and the majority continues to lose weight during radiation treatment, with a mean weight loss of approximately 10% of their body weight [ 3, 4].
The favourable outcome of 60% 3-year survival for patients with breast EPSCC compared to those with other sites may be attributed to earlier stage at presentation, since the majority of breast EPSCC in this study was limited stage disease.
This has resulted in accurate identification of vulnerable plaques that are prone to inducing ACS, which can account for the sudden onset of clinical presentation in the majority of patients with CAD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com