Suggestions(1)
Exact(3)
Three patients did not have an INR determined from the presentation sample.
In three patients with ALL (= 25%) we reproducibly detected identical clonotypic marker in the presentation sample and in the neonatal blood spot on the Guthrie card.
Table 3 also summarizes the predictive performance for miR-122, HMGB1, K18, and GLDH quantified from the first presentation sample to reflect ALI in patients admitted to the hospital emergency room later than 8 hours following overdose (n = 62).
Similar(57)
41% of presentation samples had antibodies that only recognise these N-terminal domains.
ADAMTS13 antigen levels were lower in presentation samples of patients who died (median 1.0% vs. 5.5%).
All presentation samples were taken before plasma exchange or rituximab were commenced.
We therefore analysed plasma ADAMTS13 antigen levels in 91 acquired TTP presentation samples.
We obtained presentation samples from 102 patients of whom 72 were found to be informative at the MAOA locus.
Analysis of the prognostic implications of domain specificity of anti-ADAMTS13 was performed on the 62 first presentation samples.
We demonstrated markedly reduced ADAMTS13 antigen levels in all presentation samples, median 6% normal (range 0 47%), with 84/91 patients having < 25%ADAMTS13antigenen.
Using this approach, 89/92 (97%) of TTP presentation samples were designated to have immunoreactivity against the ADAMTS13 N-terminal domains (i.e. MDTCS competed for > 5% of binding to full-length ADAMTS13).
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