Interestingly, in lung cancer cells, it has been proposed that activation of TGF-β by integrin αvβ8 involves presentation of the latent complex to the membrane metalloprotease MT1-MMP.
Because of its pre-assembled nature, the SCT presents enhanced expression and presentation of the antigenic peptide/MHC complexes at the cell surface.
The management of NPC remains burdensome as the prognosis is poor due to the late presentation of the disease and the complex nature of NPC pathogenesis.
A related curricular innovation, vertical integration, allows for the presentation of more complex cases, based specifically upon the structured acquisition and application of concepts from the preceding horizontally integrated coursework [ 8, 9].
A possible explanation for this finding is that the presentation of more complex information about autism via the visual (images, diagrams, video and animation) and auditory (sounds and narration) channels in the CAL package may increase the efficiency of the participants' working memory.
The monochromatic colour scheme was suited to the presentation of complex, multiple views of the object, which was reduced to overlapping opaque and transparent planes.
The increasing numbers of older persons and the presentation of more complex constellations of chronic diseases has contributed to a growth in research examining burden of multimorbidity.
But what was extraordinary about the unorthodox presentation was the complex, shifting range of responses it provoked.
Since the presentation of CD1d lipid complex by DC to iNKT cells results in activation and the subsequent maturation of DC, we also determined whether there was any difference in the ability of DC to upregulate the co-stimulatory molecule, CD86, following i.v. delivery of α-GalCer and ThrCer analogues.
Budgerigars (Melopsittacus undulatus) and zebra finches (Taeniopygia guttata) were trained to differentially peck keys in response to the presentation of various complex stimuli.
