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In this paper, such a methodological support is proposed by introducing principles for the design, validation and presentation of process models and associated data models.
What is described as 'evaluation' in many scheme reports might better be described as monitoring and the presentation of process data.
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The mainstay of the adaptive immune system is the antigen presentation of processed peptides by antigen presenting cells (APC) [ 12, 13].
Since p41 is particularly abundant in DC, it may also limit destructive antigen processing, maximising the chance of successful presentation of processed antigen.
For effective presentation of process-specific evaluation results, we have developed an interactive matrix-based view that facilitates comparative evaluation of multiple datasets across several targeted biological processes (Fig. 6).
The indirect pathway involves presentation of processed allogeneic HLA shed from foreign cells through cell necrosis and apoptosis.
Such recognition events lead to maturation of these APC to enable presentation of processed antigen to T cells in immunogenic form, involving provision of costimulation.
The MHC-dependent presentation of processed tissue-specific self-antigens maintains peripheral (extra-thymic) tolerance but also can lead to activation of autoreactive T cells.
7-11 T cell immune responses are stimulated by the presentation of processed viral peptides (epitopes) by human leukocyte antigen (HLA) molecules to CD4+ and CD8+ T cells.
The latter is exerted by the presentation of processed antigens on major histocompatibility complex (MHC) molecules to T lymphocytes, the expression of various costimulatory proteins on the cell surface and the production of cytokines [ 1, 2].
Its pathogenic keystone is the presentation of processed gliadin peptides by human leukocyte antigen (HLA -DQ2 and -DQ8 molecules HLA -DQ2iggering andadaptive immune response against various structures of the duodenal mucosa [ 7].
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