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Late presentation of local and distant metastases is well recognized.
In this area we have also demonstrated the presence of putative dendritic cells, suggesting the potential for presentation of local antigen within the nodule.
We selected patients (from the non-radiation treatment arm) with clinically resected TNM stage I-III adenocarcinomas of the rectum and a presentation of local and/or distant recurrent disease at follow-up.
A recent systematic review designed to investigate long-term outcomes in the setting of routine clinical follow up failed to identify any trials comparing long-term results (survival/disease-free survival) in patients with clinically detected local recurrence vs symptomatic presentation of local recurrence (de Bock et al, 2004).
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Siggi Hall is actually the name of the chef (a man who has achieved international fame and who happens to have his own TV show and several cookbooks to his credit), and his creations are truly excellent for their presentation, use of local ingredients and brilliance for bringing out the best in simple ingredients.
Detection is hampered by the non-specific clinical presentation, lack of local laboratory diagnostic facilities, cross-reactions on serologic testing, and passive and inconsistent surveillance in most African countries.
In addition to the presentation of the local PG climatology, the suitability of the site in observing GEC is examined in this study.
In particular, in his presentation of stochastic, local models of the EPR/B experiment Bell (1971, p. 37) assumes that the setting of the apparatuses need not specify their entire relevant states.
More precisely, he says that the reference of a demonstrative in a context is fixed by a demonstration, which he describes as "typically, though not invariably, a (visual) presentation of a local object discriminated by a pointing".
For presentation of the local results of stroke outcome, patients were categorised at discharge using the following three pragmatic categories.
Like our study, one strategy that has been argued to improve cure rate would be to introduce systemic therapy within the neoadjuvant treatment course to eradicate occult micrometastases that might already exist at the presentation of the local disease.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com