Sentence examples for presentation machinery from inspiring English sources

LNSCs that were isolated from inflamed lymph nodes robustly upregulated expression of genes encoding cytokines, chemokines, antigen-processing and presentation machinery, and acute-phase response molecules.

The current study would contribute to our understanding of significance of abnormalities in the antigen presentation machinery of oral squamous cell carcinoma, and provide meaningful information in the design of CTL-based tumor vaccines by intra-cellular delivery system.

We show that clinical benefit is associated with high mutational and predicted neoantigen load and elevated immune signature, including a high MHC class I antigen presentation score, while absence of benefit can be linked to downregulated antigen processing and presentation machinery (APM).

Activated dendritic cells are efficient antigen presentation machinery, and this cell type is found here to be more abundant in patients with relatively active disease, consistent with correlations between autoantibody blood titer and SLE disease activity [27].

Until now it was also not known whether or not an antigen bound to the slan epitope will be taken up and delivered to the antigen presentation machinery of slanDCs.

Additionally, overall downregulation of HLA class I antigen presentation machinery (APM) was observed in NPC biopsies.

Taken together, studies performed with human pDCs suggest that an effective cross-presentation machinery is present.

Dendritic cell (DC) vaccines are an immunotherapeutic approach to cancer treatment that use the antigen-presentation machinery of DCs to activate an endogenous anti-tumor response.

Uptake of pathogenic antigens in the presence of other stimulatory signals induces DC maturation, manifested by downregulation of phagocytic receptors and upregulation of antigen-presentation machinery, and migration to lymphoid tissues to trigger secondary specific immune responses.

Specifically, these proteins could be arrayed in the presence of antigen-presentation machinery in order to assess their precise roles in the distinct stages of T cell activation, including T cell adhesion, T cell stopping, and synapse formation.

Included in this pathway are genes involved in the antigen-presenting machinery as (i) the expression of major histocompatibility complex (MHC) molecules, (ii) the mechanism of cross-presentation, and (iii) the interaction of antigen-presenting cells.