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Modified Goldman score ≤1 Non-ischaECGc ECG Presentation high-sensitivity troponin T <14 ng/L Modified Goldman score >1 Ischaemic ECG Presentation high-sensitivity troponin T ≥14 ng/L Secondary index tests were the detection limits for hs-cTnT (5 ng/L and 3 ng/L) and non-ischaemic ECG at presentation.
Clinical comparisons between the early use (2 h after presentation) of high sensitivity cardiac troponin T (hs-cTnT) and I (hs-cTnI) assays for the diagnosis of AMI have not been reported.
Presentation of the high sensitivity wake-up radio circuit design and implementation that utilizes On-Off Keying (OOK) demodulation, low data rate and FEC to achieve target high sensitivity of -122 dBm and long communication range of 1 km.
Here we report the results pertaining to the hypothesis that a single use of the high sensitivity troponin T assay at presentation is sensitive enough to allow the safe exclusion of acute myocardial infarction.
The above results suggest that if low cut-off values are used a single measurement of high sensitivity troponin T at presentation might be sufficient to rule out acute myocardial infarction.
In the study by Body et al, 195 (27.7%) of the included 703 patients had undetectable (<3 ng/L) high sensitivity troponin T concentrations at presentation and none of them was diagnosed as having myocardial infarction.
However, a clinically applicable protocol that allows the discharge of a significant proportion of patients after just a single high sensitivity troponin blood draw at presentation to the emergency department remains an attractive yet elusive goal.
We included in the meta-analyses reported here only those studies reporting the diagnostic accuracy of the high sensitivity troponin T assay at the patient's presentation to the emergency department and using pre-specified positivity thresholds.
As many as 46% of the children with bacteraemia did not have fever at presentation to the hospital and no clinical parameters predicted bacteraemia with high sensitivity and specificity.
26 Using high sensitivity troponin alone it may be possible to exclude AMI within 60 180 min of presentation.
Current diagnostic technology, including high sensitivity troponin assays, has imperfect sensitivity and specificity for acute coronary syndromes at the time of initial presentation to the emergency department.
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